New Delhi: According to a new study, insulin resistance, which has already been related to 31 different diseases, is also connected with an increased risk of early mortality in women.
The origins of insulin resistance are not entirely understood, but excess weight and a lack of physical activity are regarded to be the primary contributors.
To learn more, Jing Wu of the Department of Endocrinology at Shandong Provincial Hospital in China and colleagues examined data from the UK Biobank, which contains genetic, medical, and lifestyle data supplied by over 500,000 people in the UK.
The TyG index, a marker of insulin resistance, was calculated for each participant based on blood sugar and fat levels, including cholesterol.
The TyG index values varied from 5.87 to 12.46 units, averaging 8.71 units.
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According to a study published in the journal Diabetologia, participants with a higher TyG score, and hence a higher level of insulin resistance, at the start of the trial tended to be men, older, less active, smokers, and obese.
After following the participants’ health for an average of 13 years, the researchers were able to correlate insulin resistance to 31 diseases.
Insulin resistance was linked to an increased chance of acquiring 26 of these conditions, including sleep disturbances, bacterial infections, and pancreatitis, with a higher level of insulin resistance indicating a higher likelihood of the illness.
In females, every one unit increase in insulin resistance was related with an 11% increased risk of death over the research period.
Insulin resistance was found to be related to all-cause mortality in females, but no relation was discovered for guys.
According to the study, every one-unit rise in insulin resistance increased the incidence of sleep disturbances by 18%, bacterial infections by 8%, and pancreatitis by 31%.
“We have shown that by assessing the degree of insulin resistance, it is possible to identify individuals at risk of developing obesity, hypertension, heart disease, gout, sciatica and some other diseases,” said Wu.
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–IANS
Photo: Xinhua/Purbu Zhaxi/IANS
